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As a result, senescent microglia secrete a range of SASP components, IL-6, IL-8, MMP3, MMP12, CXCL1, CXCL2, and CXCL10 (Cook et al., 2022)

As for those metabolites that contribute to the pathophysiology of the disease, such as UTs and TMAO, future investigations should focus on the development of inhibitors

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Elucidation of the ginsenoside Rh1 pharmacokinetic profile and improved delivery systems warrants further investigation

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ix) enantiospecific synthesis from non-racemic precursorsa synthetic technique whereby the desired enantiomer is obtained from non-chiral starting materials and where the stereochemical integrity is not or is only minimally compromised over the course of the synthesis