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No direct pharmacological link exists between GLP-1/GIP medicines and B12 deficiency, but concurrent metformin use (common in diabetes) is established to reduce B12 absorption

5-Amino-1MQ inhibits NNMT activity, preserving nicotinamide for NAD+ synthesis and preserving SAM for epigenetic methylation producing a metabolic state in pre-clinical models that has been described as functionally resembling caloric restriction or elevated physical activity at the cellular level

Since telomeres shorten each time a cell dividesand telomerase activity declines with agethe theory is that Epitalon could lead to longer telomeres that would theoretically slow your cellular aging clock

This is due to the fact that B12 enables the release of energy by helping your body absorb folic acid

Nutrients 15 , 4462 (2023)

MOTS-c (Mitochondrial ORF of the 12S rRNA Type-C) is a naturally occurring mitochondria-encoded bioactive peptide first identified in 2015 by Lee et al