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Treatment of hepatocellular carcinoma cells with a Cu(II) complex containing a triphenyl-phosphine (TPP) ligand, [Cu(ttpy-tpp)Br 2 ]Br, induced significant ROS generation, which resulted in disrupted mitochondrial membrane potential, the aggregation of Bax in mitochondria, and the release of cytochrome c (Shao et al

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Amino acid consumption and production patterns reflect protein synthesis, energy metabolism, and cellular signaling processes occurring within developing embryos [411, 412]

Cells overexpressing HRASV12 or cyclin E1 accumulate R-loops during S and G2 phases of the cell cycle To investigate the molecular mechanisms underlying R-loop formation induced by overexpression of HRASV12 or cyclin E1, we used a U2OS T-REx cell line conditionally expressing catalytically inactive RNase H1 fused to green fluorescent protein [RNH1(D210N)-GFP] 32

Release the water slowly, letting it run down the side of the vial