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[32], activation of this pathway suppresses pro-inflammatory cytokine production via NF-B inhibition and promotes the synthesis of prostaglandin D2, which in turn further attenuates NF-B signaling and associated inflammatory cascades [40]

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Essential for DNA Repair & Cellular Health

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664 Epigenetic regulators frequently exhibit aberrant expression in tumors that have developed resistance to targeted therapy, highlighting their role in the emergence of resistance to such treatments

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[3] This is named for Jonathan Hutchinson

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Aging Cell 20 , e13334 (2021)

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