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However, if saturated fatty acids accumulate in excess in cells, they become toxic and induce the generation of ROS, endoplasmic reticulum stress and NLRP3 inflammasome activation, which are all associated with a pro-inflammatory macrophage phenotype (Legrand-Poels et al., 2014)

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This method bypasses the gastrointestinal system, allowing for direct delivery into the bloodstream

Institutions planning multi-month animal studies need consistent batch-to-batch quality making supplier documentation (COA, batch traceability) a selection criterion rather than an afterthought

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Melatonin, secreted by the pineal gland in response to darkness, plays a key role in maintaining circadian homeostasis and exhibits broad oncostatic properties 19