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Beyond their role in ion regulation through membrane channels, astrocytes also secrete small extracellular vesicles that contribute to recovery after spinal cord injury and promote synapse formation via fibulin-2TGF- signaling

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However, when ER stress is persistent and severe, UPR is insufficient to restore ER function, it promotes cell apoptosis by upregulating the expression of GADD153/CHOP, by activating caspase-12, and by inhibiting Bcl-2 expression

Importantly, white blood cell and lymphocyte levels remained stable for the duration of the 8-week study, indicating that this approach spares the adaptive immune system

Psychopharmacology (Berl) 130 : 269275 Meloni D, Gambarana C, De Montis MG, Dal Pr P, Taddei I, Tagliamonte A

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