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Suramin, a century-old drug used to treat African sleeping sickness and river blindness, can effectively inhibit SARS-CoV-2 polymerase activity with at least 20-fold more activity than RDV-3Pi in biochemical assays and inhibits viral replication in vitro 141

Of 34,017 Mda5 -/- aged cells output by cellranger count, 18,248 were singlets, and 12,084 cells were retained after filtering for further analysis

Subramanya SB, Venkataraman B, Almarzooqi S, Raj V, Subramanian VS, Bhongade BA

14,15 On the other hand, in a recent study by Parkinson at al., lysine is found to be much more abundant in the human skin proteome than cysteine

Available online at: (Accessed June 9, 2025)

72 h post supernatant transfer, cells were lysed to analyse replication in infected cells