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On the one hand, it is believed that hypoxia can cause the activation of NOX enzymes, LOX-1, etc., and impair mitochondrial redox homeostasis in pulmonary vascular cells, which reduces the threshold for inducing ferroptosis (this death effect can occur at low iron levels) [152, 153]

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Nowinski, WL, Fang, A and Nguyen, BT Schaltenbrand-Wahren/Talairach-Tournoux brain atlas registration, in Medical Imaging 1995: Image Display , 2431: SPIE, pp

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