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Cells were treated with indicated concentrations (0, 0.2, 0.5, 2, 5, 10 mmol/L) of PhS for 24 hours and then treated with hydrogen peroxide (0, 10, 20 mol/L) for 5 hours

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For practical purposes, the conversion of DCA to glyoxylate determines the pharmacokinetics of elimination of DCA, thus knowledge of the factors that influence the rate and extent of GSTZ1-1-catalyzed DCA metabolism in people is important for safe and effective dosing of patients

The inclusion of participants experiencing these hormonal changes may be another limitation of the study

No adverse drug effects were reported

During energy production, ATP is degraded into ADP (adenosine diphosphate) and an inorganic phosphate molecule (Pi), which provides energy to fuel metabolic activities