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PLoS One 5:e14297

As a result, incomplete or broken bricks accumulate inside the factory, causing machinery breakdown (ineffective erythropoiesis) and poor output (anemia), while the factory expands unsustainably to meet demand (marrow expansion), leading to structural deformities and further strain

Vitamin B12 is found mostly in animal products, like fish, meat, dairy and eggs

An enzyme called NNMT (nicotinamide N-methyltransferase) drains the NAD+ salvage pathway by methylating nicotinamide, one of NAD+'s precursors

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TB-500 is the much shorter N-acetylated fragment Ac-LKKTETQ, corresponding to residues 17 to 23 of thymosin beta-4