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Description

Absorption after i.p

Microglia resist the onset and progression of AD by degrading A and tau

W.DuranS

10.1046/j.1471-4159.2002.01041.x 181

Increased sensitivity to alcohol, medications, or environmental exposures

NNMT inhibition as a therapeutic strategy has been explored in industry pharmaceutical pipelines (including a Pfizer program for non-alcoholic fatty liver disease that was reportedly discontinued in early clinical development), but no NNMT inhibitor has reached regulatory approval to date