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Aside from SQ109, several inhibitors of MmpL3, including AU1235, ICA38, Rimonabant, NITD-349, and SPIRO, have shown a strong bactericidal ability against Mtb , and have been proven to target MmpL3 [117, 125, 128, 135]

In macrophages, DMF will notably activates NRF2 to protect the cells from oxidative stress and promote an anti-inflammatory phenotype (212)

doi: 10.1111/nuf.12316 De la Fuente, J., Lpez, M., Zapata, L., Martnez-Vicente, J

Furthermore, BPC-157 may have activated the VEGFR2-Akt-eNOS signaling pathway time-dependently

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