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In the 50s, when chemotherapy wasnt yet available, massive doses of B12 shots were given to children with a neuroblastoma tumor every two days, for 2-3 years with great success: NEUROBLASTOMA: AN EVALUATION OF ITS NATURAL HISTORY AND EFFECTS OF THERAPY, WITH PARTICULAR REFERENCE TO TREATMENT BY MASSIVE DOSES OF VITAMIN B12

Yes, I was convinced it was my thyroid was what was wrong with me, (my mother has underactive thyroid) but two years down the line of injections I'm starting to feel much better, not lost any weight mind you

While it is not a serious side effect, it can have important quality-of-life effects

In some cases, levels exceed 3,000 pg/mL

Better Mood and Mental Clarity: Helps reduce symptoms of depression and anxiety, and improves cognitive function

Oz dedicating years to studying and refining its approach, further cementing its place in weight loss strategies