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A.JohnsonM.DuH

TLR4 signals that promote the expression of MCP-1 are increased in the dorsal root ganglia of rats with paclitaxel-induced hyperalgesia, and this effect can be prevented by cotreating the animals with TLR4 antagonists during chemotherapy [116]

6 The impact of existing treatment strategies on immune-inflammatory interactions Growing evidence indicates that immune-inflammatory dysregulation plays a pivotal role in the pathogenesis of varicocele-related complications, including male infertility and erectile dysfunction (184)