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Competent yeast cells were transformed with yeast-display plasmid pCTCON2 following the Frozen EZ yeast transformation II (Zymo Research, T2001) according to the manufacturers protocol

The repeated failures of A-targeted therapies highlight the need for a paradigm shift toward multi-targeted treatment approaches that address tau pathology, neuroinflammation, oxidative stress, mitochondrial dysfunction, and synaptic degeneration

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The GPX4 activity decreased in the BSO@MOF-L group, as indicated by the changing amount of nicotinamide adenine dinucleotide phosphate over time (Additional file 1: Fig

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