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For example, testing its metal chelating ability, researchers observed a dramatic 66.03% reduction in blood lead levels in mice receiving chlorella extract (50 mg/kg/day) concurrent with lead exposure compared to lead-exposed, non-treated mice.*

J Biol Chem 277:4509945107

Meanwhile, ET-1 can also increase the glomerular permeability by targeting its receptor, resulting in the aggravating albuminuria and DN progression (Ergul, 2011)