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10.1007/s10928-021-09799-0 [DOI] [PMC free article] [PubMed] [Google Scholar] 52.Zacharias N, Podust VN, Kajihara KK, Leipold D, Del Rosario G, Thayer D, Dong E, Paluch M, Fischer D, Zheng K, Lei C, He J, Ng C, Su D, Liu L, Masih S, Sawyer W, Tinianow J, Marik J, Yip V, Li G, Chuh J, Morisaki JH, Park S, Zheng B, Hernandez-Barry H, Loyet KM, Xu M, Kozak KR, Phillips GL, Shen B-Q, Wu C, Xu K, Yu S-F, Kamath A, Rowntree RK, Reilly D, Pillow T, Polson A, Schellenberger V, Hazenbos WLW, Sadowsky J (2022) A homogeneous high-DAR antibody-drug conjugate platform combining THIOMAB antibodies and XTEN polypeptides

Moreover, stromal cells within the microenvironment can support tumor growth by providing metabolic substrates (such as glutamine and fatty acids [FAs]) or recycling metabolic waste (such as lactate), thereby forming a metabolic symbiotic network [16, 17]

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