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Chapter 22

243 Mutations in TCA cycle enzymes such as SDH can lead to metabolite accumulation (such as succinate), inhibiting prolyl hydroxylases and affecting HIF-1 stability

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We hypothesized that the targeting capacity of CTP might be mediated by a specific combination of proteins or receptors in CMs and CFs under pathological conditions

Sucede lo mismo si la produccin del propio organismo se ve alterada por trastornos metablicos (p