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Brauer GM, Stansbury JW

The adoption of the PCPA-induced insomnia model in mice has enabled researchers to delve into the molecular mechanisms underlying sleep regulation (Hong et al., 2020), exploring the intricate interplay of cytokines (Wang et al., 2022), neurotransmitters (Lv et al., 2021), and their receptors

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Other peptides or compounds may have less clinical evidence supporting their effectiveness

Overall, the trial demonstrated that once-weekly Cagrilintide induced clinically meaningful, dose-dependent weight loss in adults with overweight or obesity, with efficacy comparable or superior to liraglutide 3.0 mg