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Insulin resistance present in approximately 6580% of cases, independent of body weight, and the primary driver of the androgenic environment in the ovary.[2] Androgen excess elevated testosterone, DHEA-S, or androstenedione, driving most of the visible symptoms: hirsutism, acne, scalp hair thinning, cycle disruption

[6] Nagele P, Zeugswetter B, Wiener C, et al

The UL values only apply to niacin supplements plus niacin fortification, and they are based on the nicotinic acid-induced skin flush response

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Axelsson, Annika S., Emily Tubbs, Brig Mecham, Shaji Chacko, Hannah A

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