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Mechanistic investigations also examine gene expression profiles related to hormone signaling, lipid mobilization pathways, and hepatic metabolic processes

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Healthy volunteers (16 females and 15 males) were supplemented with 500 mg of vitamin C per day for 6 weeks, and consequently, the levels of two representative biomarkers of oxidative damage, 8-oxoguanine and 8-oxoadenine, in lymphocyte DNA were evaluated via chromatographymass spectrometry (GCMS) (Podmore et al