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Al-Badr This chapter was originally published in the book Profiles of Drug Substances, Excipients, and Related Methodology, Vol

This review highlights the biocatalyst-mediated synthesis of nicotinic-acid- and nitrile-metabolizing enzymes through state-of-the-art omics-based techniques to improve enzyme catalytic efficiency and stability via various approaches

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Fibroblast activation protein- (FAP)-positive cancer-associated fibroblasts and macrophages represent potential targets for improving the tumor immunosuppressive microenvironment [11, 127]