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An intestinal epithelial defect conferring ER stress results in inflammation involving both innate and adaptive immunity

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JAMA 325(6):568578 Yang Y, Hao C, Jiao T, Yang Z, Li H, Zhang Y, Zhang W, Doherty M, Sun C, Yang T, Li J, Wu J, Zhang M, Wang Y, Xie D, Wang T, Wang N, Huang X, Li C, Gonzalez FJ, Wei J, Xie C, Zeng C, Lei G (2025) Osteoarthritis treatment via the GLP-1-mediated gut-joint axis targets intestinal FXR signaling

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