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Tuberculosis and impaired IL-23-dependent IFN- immunity in humans homozygous for a common TYK2 missense variant

Epitalon (Epithalamin) molecular model built with Molymod Atoms & Bonds Parts Synonyms IUPAC Name: (4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(2S)-3-carboxy-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid InChI=1S/C14H22N4O9/c1-6(15)12(25)17-7(2-3-9(19)20)14(27)18-8(4-10(21)22)13(26)16-5-11(23)24/h6-8H,2-5,15H2,1H3,(H,16,26)(H,17,25)(H,18,27)(H,19,20)(H,21,22)(H,23,24)/t6-,7-,8-/m0/s1 InChIKey: HGHOBRRUMWJWCU-FXQIFTODSA-N SMILES: CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NCC(=O)O)N CAS: 64082-79-7

Four patients having recurrent diverticulitis were treated conservatively