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Glutathione is an antioxidant that is involved in inflammatory responses and immune modulation, including the modulation of redox-regulated signal transduction, regulation of cell proliferation and remodeling of the extracellular matrix

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589 Kelch-like ECH-associated protein 1 (Keap1)-nuclear factor erythroid 2-related factor 2 (Nrf2), critical for regulating anti-oxidative stress, represents a PPI targetable by covalent inhibitors

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The studys findings demonstrated that AlCl 3 causes cognitive impairment (memory and learning deficits, anxiety, and reduced locomotion) as well as oxidative stress, cholinergic impairment, and histological changes in the brains of rats