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However, as a precautionary measure, patients with severe kidney disease or those with known cyanide metabolism disorders are sometimes advised to use alternative B12 forms

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To address this gap, we propose the concept of a Dynamic Living Digital Twin framework for precision dosing in critical illness

La kalimie doit tre attentivement surveille durant les 2 premiers jours de traitement par la vitamine B12 chez les sujets prsentant une anmie mgaloblastique : une hypokalimie peut survenir en raison de l'augmentation des besoins rythrocytaires en potassium