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Insulin-like growth factor 1 long arginine 3, animal component-free Overview IGF-I long arginine 3 (LR3) binds to insulin-like growth factor 1 (IGF-I) receptor and is a potent activator of the PI3K/AKT pathway and ERK1/2 signaling

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The ubiquitinated proteins are recognized by the sorting machinery of early endosomes, which does not gather these integral proteins for being included in vesicles shipped to plasma membrane