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2025;12(21):e2414559

67,505 Ulefnersen (ION-363), an antisense therapy targeting the FUS gene, is currently in Phase III trials for FUS-ALS

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In this state, the overactivation of N-methyl-D-aspartate receptor-type channels in L-glutamate (L-glu) channels mediates a large influx of Ca 2 , leading to cellular excitotoxicity and neuronal death

However, when animals are fed diets high in protein, the protein content often exceeds their physiological needs, leading to resource wastage, increased production costs, and reduced economic efficiency (2)

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