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additionally NAD + can be generated in the mitochondria from NMNAT3 80 , whose activity has been shown to be required in cells 77 , but dispensable in vivo as NAD + can be replenished through other pathways such as import from the cytosol 81

doi:10.1016/j.fgb.2012.02.003

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Esto minimiza el riesgo de infeccin y maximiza los beneficios del tratamiento