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In a model of amyotrophic lateral sclerosis (ALS) caused by C9orf72 gene mutations, the pathogenic poly-dipeptide GA50 directly binds to and inhibits SQOR, leading to excessive NLRP3 inflammasome activation in microglia and consequent mitochondrial dysfunction ( A growing body of preclinical work supports this strategy: boosting SQOR activity or reducing H 2 S can protect the nervous system

The evidence is promising, but the research base is still building

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27 Iron overload appears to be the main driver of ferroptosis and has been shown to make many cell types more susceptible to this form of cell death

It helps generate thyroid hormones, estrogen, and progesterone, boost fertility, and strengthen immune system

That is not speculation