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Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors

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Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

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Casida J, Quistad G., (2004)

These cerebral functions are frequently defective in AD patients, and it has been suggested that AD patients carry a compromised endocannabinoid system (Basavarajappa et al