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Current strategies aimed at restoring FAO primarily involve compounds that activate the PPAR, PGC-1, and AMPK signaling pathways ( Dysregulation of the mTOR and AMPK signaling pathways has been implicated in the metabolic reprogramming of TECs during AKI

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Cleavable linkers can be divided into two broad categories: enzymatic and chemical linkers

Early detection and management of CIC are crucial for minimizing the associated morbidity and mortality

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Sulfation and glucuronidation are so-called phase II detoxification reactions, the general purpose of which is to increase the water-solubility of the substrates and, thus, to facilitate their biliary and/or urinary clearance