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10.1016/j.cmet.2021.12.004 74 SasakiK.BohnenbergerS.HayashiK.KunkelmannT.MuramatsuD.PhrakonkhamP.et al (2012a)

Conclusion: Certain combinations of common genetic variants in cholestasis-associated genes show an association with cholestatic enzyme profiles and may be causally involved in the development of previously unexplained cholestatic liver injury

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Tirzepatide users commonly report that high-fat foods cause the worst nausea and bloating, because the slowed gastric emptying means fat sits in the stomach longer