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If youve experienced severe allergy-like symptoms such as hives, difficulty breathing, low blood pressure, and severe diarrhea and your doctor diagnoses you with allergies you may actually have mast cell activation syndrome

The p K a of the histidine imidazole group is 6.5, and thus histidine behaves as hydrophobic residue at neutral pH, whereas it is protonated and behaves as a basic peptide in the slightly acidic endosomal milieu

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"MOTS-c: A promising mitochondrial-derived peptide for therapeutic exploitation." 14, 1120533

However, it can also slowly be intravenous or subcutaneous (injected into a vein or under the skin)

Cocaine induces cardiac dysrhythmias such as sinus tachycardia, wide complex supraventricular tachycardia, atrial fibrillation, and ventricular tachycardia