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2024A515012151), the Guangdong Provincial Key Laboratory of Fangzheng (Grant No

The variable clinical manifestations of ataxia among individuals are influenced by multiple factors such as location, size, and etiology of the lesions (Karamazovova et al., 2023)

Multiple dose levels (1, 4, 8, 12 mg) were tested in Phase 2, with the Phase 3 dose selection to be refined based on efficacy-tolerability balance

& Lehmann, F

Furthermore, at therapeutic levels, varenicline does not inhibit human renal transport proteins, as demonstrated by preclinical studies

Dosages are reported as mg/day of extract where available, with key phytochemical standardization noted when specified in the original studies