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PMID: 23 JicklingGCLiuDAnderBPStamovaBZhanXSharpFR

We reviewed indexed literature reviews in PubMed database, using the following search string (January 2020): (Attention deficit hyperactivity disorder [Title] OR ADHD [Title] OR Attention-Deficit/Hyperactivity Disorder [Title]) AND (pathogenesis [[Title/Abstract] OR pathophysiology [Title/Abstract] OR molecular [Title/Abstract]) AND Review [ptyp]

In fact, these anti-inflammatory effects have been demonstrated in mouse microglia, macrophages, monocytes, and astrocytes (Kobayashi et al., 2016

Phiwchai I, Yuensook W, Sawaengsiriphon N, Krungchanuchat S, Pilapong C (2018) Tannic acid (TA): a molecular tool for chelating and imaging labile iron

Specifically, bromelain has been shown to inhibit the NF-B (nuclear factor-kappa B) pathway, which acts as a master switch for inflammation in the body