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Epigenetic mechanisms play an important role in the initiation and development of PCa, with gene-specific hypermethylation and hypomethylation being associated with PCa (Willard and Koochekpour, 2012)

References Aggarwal S, Verma SS, Aggarwal S, Gupta SC (2021) Drug repurposing for breast cancer therapy: old weapon for new battle

Encapsulation strategies not only protect DNA from enzyme degradation and immune recognition but also maintain the structural integrity of genetic material in transit [221]

Oral and topical forms have few possible side effects, usually mild stomach upset or rare irritation, and one study used 300 milligrams a day for four months with good tolerance

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They established associations with non-codeletion of 1p19q, higher WHO grades, wild-type IDH, and immunosuppressive tumor microenvironments (89)