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However, during mastitis, the increased ROS levels can overwhelm these natural defenses, leading to oxidative stress ( Figure 2 )

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Other observations of a high Ferric/ferrous ratio (Zhao et al., 2023) and abundance of oxidised glutathione (Paik et al., 2003) at the SN microenvironment also support the hypothesis that -synuclein fibrillation is conducive under oxidising conditions

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Metformin induces microRNA-34a to downregulate the Sirt1/Pgc-1alpha/Nrf2 pathway, leading to increased susceptibility of wild-type p53 cancer cells to oxidative stress and therapeutic agents

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The effectiveness of QDs purification was confirmed by measuring the pH of QDs solution, which should be equal to the pH of the dialysate (~ pH = 7.4)

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