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Description

190 In mammals, the sirtuin family comprises seven proteins (SIRT1SIRT7), each with distinct tissue specificity, subcellular localization, enzymatic activity, and target genes

The oxidized form of glutathione (glutathione disulfide), which is generated during the reduction of hydroperoxides by GPX4, is recycled by glutathione reductase and NADPH/H +

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For instance, thyroid cancer is associated with the increased presence of Clostridiaceae , Neisseria , and Streptococcus , whereas in patients with thyroid nodules, a relative increase of Streptococcus and Neisseria compared to healthy controls was observed (235)