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Clinical studies using fluorodeoxyglucose FDG and positron emission tomography (FDG-PET) imaging studies in subjects with AD have shown reduced glucose transport and glucose metabolism in the areas most affected by AD (88)

Haplopine ameliorates 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and Tnf-A/Ifn--induced inflammation in human keratinocyte

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Acknowledgements We would like to thank the families of individuals with autism for the thoughtful donation of post-mortem tissues to the Autism Tissue Program at the Harvard Brain Tissue Resource Center, Belmont, MA,USA, and the NICHD Brain and Tissue Bank for Developmental Disorders at the University of Maryland, Baltimore, MD, USA

535,536 Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an essential regulator of LDL-C metabolism