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In a medically supervised, quality-controlled context with appropriate screening and protocol design, it is generally viewed as a reasonable regenerative strategy and is commonly reported as well tolerated

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Safe use requires routine monitoring of weight, A1C, renal function, and AEs, particularly during dose escalation

Ethics statement The animal studies were approved by this study was approved by the Research Committee of the Animal Policy and Welfare Committee of Liaocheng University (No

Identifying research gaps, the review highlights the importance of clinical trials to verify therapeutic benefits