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We found that GlutEE treatment accelerated ferroptosis in multiple NSCLC cells (Figure 2B), while glutamine starvation, which depleted intracellular glutamate (Figure S2D), or treatment with the transaminase inhibitor AOA could rescue ferroptosis (Figure 2C)

AD patients with CAA show reduced Complex IV activity and increased mtDNA damage in brain microvessels compared to those without CAA

Fisetin as a caloric restriction mimetic protects rat brain against aging induced oxidative stress, apoptosis and neurodegeneration

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Conclusion Glutathione is one of the most powerful antioxidants produced by the body