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5-Amino-1MQ has been studied as an NNMT inhibitor in the context of adipocyte metabolism and NAD+ salvage regulation (Neelakantan et al., 2018, ACS Medicinal Chemistry Letters)

Initial plasma concentrations of IL-1B, IL-1RA, IL-7, IL-8, IL-9, IL-10, basic FGF, GCSF, GMCSF, IFN, IP10, MCP1, MIP1A, MIP1B, PDGF, TNF and VEGF were higher in ICU and non-ICU patients than in healthy adults

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Functional polymorphisms in Nrf2: implications for human disease