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HSP-70, a chaperone protein within the heat shock protein family, is produced by macrophages, smooth muscle cells, endometrial cells, dendritic cells, and vascular endothelial cells

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During physiological conditions, neurons and astrocytes have a coordinated functional relationship that ensures proper information flow, and each contributes to synaptic transmission by releasing neurotransmitters (by presynaptic neurons) or gliotransmitters (by astrocytes

The cellular basis for memory and regulation of motivation associated with the nucleus accumbens may also be improved via NAC-induced neuronal activation of cysteine-glutamate exchange, augmented by the indirect effects of NAC on the metabolic glutamate receptors, mGluR2/3 and mGluR5, as reported for amelioration of cocaine-induced disruption of memory and regulation of motivation in rodents [36]