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APRI and Fib4 estimates of fibrosis have proven useful for helping estimate the degree of fibrosis in other liver disorders, and some preliminary ranges for patients with WD were proposed (Paternostro et al Liver Int 2020)

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Mrbe UM, Jrgensen PB, Fenton TM, von Burg N, Riis LB, Spencer J, et al

In the spectra recorded in methanol solutions this band is located at 260 nm (VA) and 258 nm (isoVA)

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After selecting the most suitable incubation time of 72 hours, VOCs were measured in triplicate for each condition