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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

While its still early in human research, the pathways it targets are well-documented in metabolic science, and the results so far are promising

It drives two enzyme reactions that matter clinically

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Some studies suggest that it may help in reducing body fat, although its effectiveness can vary from person to person

However, clearance can markedly affect the extent of availability because it determines the extraction ratio (equation [8a])