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Thus, targeting the NRF2-ARE axis can provide long-lasting and comprehensive neuronal protection, rendering it highly attractive for the treatment of neurodegenerative diseases

Its just dropping a bomb on the system, which is fine when youve got runaway inflammation and your foot looks like a cantaloupe, as it did in my case, but not so much in the healing process

Acknowledgments The authors gratefully acknowledge the University Institute of Food Science & Technology, The University of Lahore, Pakistan

The toxicity mechanism of A aggregates remains uncertain, but different perspectives exist: 77,128 A might cause AD pathology through the loss of physiological functions during the aggregation process

10.1016/j.tox.2021.152894 Toxicology

In recent years, the development of different targeted drug delivery formulations and administration routes of catalpol maximise its efficacy has become a major focus of research