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Zepbound is indicated if: You are obese (body mass index (BMI) of 30 or more) or, Overweight (BMI 27 or more) and you have at least one weight-related condition, such as diabetes, hypertension (high blood pressure), hypercholesterolemia, or heart disease, or, You have moderate to severe obstructive sleep apnea (OSA) due to obesity You can get a Mounjaro prescription if you have type 2 diabetes

10.1073/pnas.96.12.7110 Proc

[DOI] [PubMed] [Google Scholar] 398.Forrest K.Y., Stuhldreher W.L

Interestingly, a link between DNA methylation changes and presence of ROS has been suggested with the finding that increased ROS leads to oxidation of 5mC into 5hmC [62], likely leading to changes in gene expression regulation