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These changes collectively contribute to a breakdown in immune homeostasis, the Treg/Th17 balance shifts toward a pro-inflammatory state, Tfh cells promote B cell hyperactivation and autoantibody production, and mTOR pathway activation enhances glycolytic metabolism and inflammatory cytokine release in immune cells, ultimately leading to multitissue injury

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[DOI] [PMC free article] [PubMed] [Google Scholar] 90.Szajewska H., Wanke M., Patro B

Further, they can regulate the activities of most enzymes and cell receptors and have significant anti-allergic effects (Table 1)

However, the protein isolates had slightly higher ash contents (4.219.90%) than the defatted meals (5.46.6%)

"Phytochelatin synthase genes from Arabidopsis and the yeast Schizosaccharomyces pombe"