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C.SchmidtK.PfeifferS.MayerB

The tumor-promoting activity mediated by H 2 O 2 manifests through the promotion of epithelial-to-mesenchymal transition (EMT) and the formation of the tumor microenvironment (TME) by tumor-associated macrophages

Among upstream regulators of ferroptosis in IBD, hypoxia-inducible factors (HIFs) occupy a unique position by integrating hypoxic stress, iron homeostasis, and inflammatory signaling, thereby setting the threshold at which epithelial ferroptosis is triggered

Schoffnegger, D., Heinke, B., Sommer, C

It helps to focus on small wins, like when the fatigue or nausea subsides after a few weeks

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